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Joined 2 years ago
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Cake day: March 31st, 2025

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  • DCM is also about the only good solvent left that is also resistant to lewis acids. I think that some people were pushing for benzotrifluoride as a replacement, but it just straight up doesn’t work as well where i tried it

    Tbf before “do it in DCM” was “do it in CCL4” or “do it in benzene”, DCM just works without nuking operator’s liver

    Lots of these new green solvents are also annoyingly polar so perhaps they can be used as replacements of other polar solvents but not anything else. I’m not using cyrene, fuck that

    TFA is used because it works and is shelf-stable. Replacements like HCl in ether or ethyl acetate are bitch to make and when these can be bought, they have to be refrigerated all the way. Straight up not worth the effort on small scale















  • waaaaay less impressive when you take a look inside

    Once Evo got familiar with the genomes of Phi X-174 and its kin, the researchers prompted the model to write new versions of its own. Evo generated 700,000 potential versions; the scientists pursued only the ones that looked as if they had the best odds of succeeding.

    They ended up making DNA molecules from 285 of Evo’s suggested sequences. […] All told, they discovered that 16 of Evo’s genomes produced viable new viruses.

    Dr. Crook cautioned that Evo’s viruses were not radically new creations. They tend to be very similar to natural species, relying on the same underlying biology.

    look out for breathless boosters “warning” everyone that ai will kill us all and it’s definitely not used as a marketing strategy